Recombinant Human GDF15 Protein, GST-tagged

• Cat.No.: GDF15-4822H
• Product Overview: Human GDF15 full-length ORF ( AAH00529.1, 31 a.a. - 308 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Bone morphogenetic proteins (e.g., BMP5; MIM 112265) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 56.21 kDa
• AA Sequence: SLAEASRASFPGPSELHSEDSRFRE LRKRYEDLLTRLRANQSWEDSNTDL VPAPAVRILTPEVRLGSGGHLHLRI SRAALPEGLPEASRLHRALFRLSPT ASRSWDVTRPLRRQLSLARPQAPAL HLRLSPPPSQSDQLLAESSSARPQL ELHLRPQAARGRRRARARNGDHCPL GPGRCCRLHTVRASLEDLGWADWVL SPREVQVTMCIGACPSQFRAANMHA QIKTSLHRLKPDTVPAPCCVPASYN PMVLIQKTDTGVSLQTYDDLLAKDC HCI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GDF15 growth differentiation factor 15 [ Homo sapiens ]
• Official Symbol: GDF15
• Synonyms: GDF15; growth differentiation factor 15; growth/differentiation factor 15; MIC 1; MIC1; NAG 1; PDF; PLAB; prostate differentiation factor; PTGFB; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; MIC-1; NAG-1; GDF-15
• Gene ID: 9518
• mRNA Refseq: NM_004864
• Protein Refseq: NP_004855
• MIM: 605312
• UniProt ID: Q99988