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Recombinant Human GDF15 protein(Ala197-Ile308), His-tagged

Cat.No. : GDF15-20H
Product Overview : Recombinant Human GDF15 (NP_004855.2) (Ala197-Ile308) was expressed in Yeast with a polyhistidine tag at the N-terminus.
  • Specification
  • Gene Information
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Source : Yeast
Species : Human
Tag : N-His
Protein length : Ala197-Ile308
Form : Lyophilized from sterile 50mM HAc, pH 2.9. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant mature form of human GDF15 consists of 122 amino acids and predicts a molecular mass of 13.7 kDa. As a result of glycosylation, it migRates as an approximately 18.2 kDa band in SDS-PAGE under reducing conditions.
Purity : > 90 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : GDF15 growth differentiation factor 15 [ Homo sapiens ]
Official Symbol : GDF15
Synonyms : GDF15; growth differentiation factor 15; growth/differentiation factor 15; MIC 1; MIC1; NAG 1; PDF; PLAB; prostate differentiation factor; PTGFB; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; MIC-1; NAG-1; GDF-15;
Gene ID : 9518
mRNA Refseq : NM_004864
Protein Refseq : NP_004855
MIM : 605312
UniProt ID : Q99988

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does GDF15 play in cardiovascular diseases, particularly in heart failure and atherosclerosis? 08/14/2022

GDF15 influences cardiovascular health, impacting heart failure progression and atherosclerotic processes.

How does GDF15 influence inflammatory processes and immune responses in chronic diseases? 07/17/2022

GDF15 modulates inflammatory and immune responses, crucial in the context of chronic diseases.

How does GDF15 contribute to tissue repair and fibrosis in organs like the liver and kidneys? 10/16/2021

GDF15 contributes to tissue repair and fibrosis, particularly in liver and kidney pathologies.

What is the impact of GDF15 on cancer development and progression, especially in terms of tumor microenvironment modulation? 05/18/2021

GDF15 affects cancer development by altering the tumor microenvironment and influencing tumor cell behavior.

How do alterations in GDF15 expression impact aging and age-related pathologies? 07/14/2018

Changes in GDF15 expression are linked to aging and age-related diseases, affecting various physiological processes.

How does GDF15 regulate energy metabolism and appetite in the context of obesity and metabolic disorders? 04/21/2018

GDF15 is involved in regulating energy metabolism and appetite, playing a key role in obesity and metabolic syndromes.

What are the mechanisms by which GDF15 affects cellular stress responses and apoptosis? 03/05/2018

GDF15 is involved in cellular stress responses, influencing apoptosis and cell survival mechanisms.

Customer Reviews (3)

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Reviews
03/19/2021

    Dependable protein purification, consistent and cost-effective.

    07/29/2019

      Precise mass spectrometry analysis, key for proteomics research.

      02/22/2019

        Great antibody validation, enhances our immunoprecipitation experiments.

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