Recombinant Human GET3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GET3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : GET3-3520H
Product Overview : ASNA1 MS Standard C13 and N15-labeled recombinant protein (NP_004308) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 38.8 kDa
AA Sequence : MAAGVAGWGV EAEEFEDAPD VEPLEPTLSN IIEQRSLKWI FVGGKGGVGK TTCSCSLAVQ LSKGRESVLI ISTDPAHNIS DAFDQKFSKV PTKVKGYDNL FAMEIDPSLG VAELPDEFFE EDNMLSMGKK MMQEAMSAFP GIDEAMSYAE VMRLVKGMNF SVVVFDTAPT GHTLRLLNFP TIVERGLGRL MQIKNQISPF ISQMCNMLGL GDMNADQLAS KLEETLPVIR SVSEQFKDPE QTTFICVCIA EFLSLYETER LIQELAKCKI DTHNIIVNQL VFPDPEKPCK MCEARHKIQA KYLDQMEDLY EDFHIVKLPL LPHEVRGADK VNTFSALLLE PYKPPSAQTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GET3 guided entry of tail-anchored proteins factor 3, ATPase [ Homo sapiens (human) ]
Official Symbol : GET3
Synonyms : GET3; guided entry of tail-anchored proteins factor 3, ATPase; ARSA1; ASNA1; TRC40; ARSA-I; ASNA-I; ATPase GET3; arsA arsenite transporter, ATP-binding, homolog 1; golgi to ER traffic 3 homolog; transmembrane domain recognition complex 40 kDa ATPase subunit; EC 7.3.2.7
Gene ID : 439
mRNA Refseq : NM_004317
Protein Refseq : NP_004308
MIM : 601913
UniProt ID : O43681

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