Recombinant Human GFAP Protein, His-tagged
Cat.No. : | GFAP-01H |
Product Overview : | Recombinant human full length GFAP protein with a polyhistidine tag at the C-terminus was expressed in human 293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Molecular Mass : | 52.9 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/μg of protein (<1EU /μg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
Storage Buffer : | Purified protein formulated in a sterile solution of PBS buffer, pH 7.2, without any preservatives |
Gene Name : | GFAP glial fibrillary acidic protein [ Homo sapiens (human) ] |
Official Symbol : | GFAP |
Synonyms : | GFAP; glial fibrillary acidic protein; ALXDRD; glial fibrillary acidic protein |
Gene ID : | 2670 |
mRNA Refseq : | NM_002055 |
Protein Refseq : | NP_002046 |
MIM : | 137780 |
UniProt ID : | P14136 |
Products Types
◆ Recombinant Protein | ||
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Gfap-3191M | Recombinant Mouse Gfap Protein, Myc/DDK-tagged | +Inquiry |
GFAP-1399M | Recombinant Mouse GFAP Protein (1-430 aa), His-tagged | +Inquiry |
GFAP-3535M | Recombinant Mouse GFAP Protein, His (Fc)-Avi-tagged | +Inquiry |
GFAP-2201H | Recombinant Human GFAP Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
GFAP-526H | Native Human GFAP protein | +Inquiry |
GFAP-18P | Native Porcine GFAP Protein | +Inquiry |
GFAP-171B | Native bovine GFAP | +Inquiry |
◆ Lysates | ||
GFAP-5955HCL | Recombinant Human GFAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (7)
Ask a questionGFAP is crucial for maintaining the structure and function of astrocytes in the CNS.
GFAP is used as a biomarker to assess astrocyte activation and neural damage.
It forms intermediate filaments, providing mechanical support and stability to astrocytes.
It plays a protective role, participating in the glial scar formation post-injury.
Dysregulation of GFAP can lead to impaired astrocyte function and neural dysfunction.
Increased GFAP levels are observed in gliosis, neurodegenerative diseases, and brain injuries.
Therapeutic interventions may aim at modulating GFAP expression to mitigate neural damage.
Customer Reviews (3)
Write a reviewFast, efficient customer service.
Product works great in assays.
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