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Native Human GFAP protein

Cat.No. : GFAP-526H
Product Overview : Native Human GFAP protein purified from Human Brain.
Description : This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Source : Human Brain
Species : Human
Form : Lyophilized from urea, sodium phosphate, and sodium bicarbonate.
Molecular Mass : 43,000-49,000
Purity : ≥90% by SDS-PAGE
Notes : Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Stability : Following reconstitution, aliquot and freeze (-20 centigrade). Stock solutions are stable for up to 3 months at -20 centigrade.
Storage : Storage at -20 centigrade.
Reconstitution : dH2O (1 mg/ml)
Gene Name : GFAP glial fibrillary acidic protein [ Homo sapiens ]
Official Symbol : GFAP
Synonyms : GFAP; glial fibrillary acidic protein; FLJ45472; intermediate filament protein; FLJ42474;
Gene ID : 2670
mRNA Refseq : NM_001131019
Protein Refseq : NP_001124491
MIM : 137780
UniProt ID : P14136
Chromosome Location : 17q21
Pathway : Nuclear signaling by ERBB4, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by ERBB4, organism-specific biosystem;
Function : integrin binding; structural constituent of cytoskeleton;

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