Native Human GFAP protein
Cat.No. : | GFAP-526H |
Product Overview : | Native Human GFAP protein purified from Human Brain. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | Human Brain |
Species : | Human |
Form : | Lyophilized from urea, sodium phosphate, and sodium bicarbonate. |
Molecular Mass : | 43,000-49,000 |
Purity : | ≥90% by SDS-PAGE |
Notes : | Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. |
Stability : | Following reconstitution, aliquot and freeze (-20 centigrade). Stock solutions are stable for up to 3 months at -20 centigrade. |
Storage : | Storage at -20 centigrade. |
Reconstitution : | dH2O (1 mg/ml) |
Gene Name : | GFAP glial fibrillary acidic protein [ Homo sapiens ] |
Official Symbol : | GFAP |
Synonyms : | GFAP; glial fibrillary acidic protein; FLJ45472; intermediate filament protein; FLJ42474; |
Gene ID : | 2670 |
mRNA Refseq : | NM_001131019 |
Protein Refseq : | NP_001124491 |
MIM : | 137780 |
UniProt ID : | P14136 |
Chromosome Location : | 17q21 |
Pathway : | Nuclear signaling by ERBB4, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by ERBB4, organism-specific biosystem; |
Function : | integrin binding; structural constituent of cytoskeleton; |
Products Types
◆ Recombinant Protein | ||
GFAP-3535M | Recombinant Mouse GFAP Protein, His (Fc)-Avi-tagged | +Inquiry |
GFAP-1399M | Recombinant Mouse GFAP Protein (1-430 aa), His-tagged | +Inquiry |
GFAP-2164R | Recombinant Rat GFAP Protein, His (Fc)-Avi-tagged | +Inquiry |
GFAP-4847H | Recombinant Human GFAP Protein, GST-tagged | +Inquiry |
Gfap-3191M | Recombinant Mouse Gfap Protein, Myc/DDK-tagged | +Inquiry |
◆ Native Protein | ||
GFAP-171B | Native bovine GFAP | +Inquiry |
GFAP-18P | Native Porcine GFAP Protein | +Inquiry |
◆ Lysates | ||
GFAP-5955HCL | Recombinant Human GFAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGFAP is crucial for maintaining the structure and function of astrocytes in the CNS.
GFAP is used as a biomarker to assess astrocyte activation and neural damage.
It forms intermediate filaments, providing mechanical support and stability to astrocytes.
It plays a protective role, participating in the glial scar formation post-injury.
Dysregulation of GFAP can lead to impaired astrocyte function and neural dysfunction.
Increased GFAP levels are observed in gliosis, neurodegenerative diseases, and brain injuries.
Therapeutic interventions may aim at modulating GFAP expression to mitigate neural damage.
Customer Reviews (3)
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Product works great in assays.
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