Recombinant Human GFUS Protein, His-tagged

• Cat.No.: GFUS-15H
• Product Overview: Recombinant human GFUS protein (2-321) with a N-terminal His-tag was expressed in E. coli.

Specification

• Description: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol
• Molecular Mass: 37.98 kDa
• Protein length: 2-321
• Purity: ≥90% estimated by SDS-PAGE
• Applications: WB, ELISA
• Stability: ≥ 1 year
• Storage: Store at -80 centigrade

Gene Information

• Gene Name: GFUS GDP-L-fucose synthase [ Homo sapiens (human) ]
• Official Symbol: GFUS
• Synonyms: GFUS; GDP-L-fucose synthase; FX; P35B; TSTA3; SDR4E1; GDP-L-fucose synthase; 3-5 epimerase/4-reductase; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; red cell NADP(H)-binding protein; short chain dehydrogenase/reductase family 4E, member 1; testis tissue sperm-binding protein Li 45a; tissue specific transplantation antigen 3; tissue specific transplantation antigen P35B
• Gene ID: 7264
• mRNA Refseq: NM_001317783
• Protein Refseq: NP_001304712
• MIM: 137020
• UniProt ID: Q13630