Recombinant Human GFUS Protein, His-tagged GFUS-15H

Recombinant Human GFUS Protein, His-tagged


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Recombinant Human GFUS Protein, His-tagged

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Cat.No. : GFUS-15H
Product Overview : Recombinant human GFUS protein (2-321) with a N-terminal His-tag was expressed in E. coli.
Description : Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Source : E. coli
Species : Human
Tag : His
Form : 50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol
Molecular Mass : 37.98 kDa
Protein length : 2-321
Purity : ≥90% estimated by SDS-PAGE
Applications : WB, ELISA
Stability : ≥ 1 year
Storage : Store at -80 centigrade

Lane 1: MW Markers, Lane 2: GDP-L-Fucose Synthase (8 µg), Lane 3: GDP-L-Fucose Synthase (4 µg), Lane 4: GDP-L-Fucose Synthase (2 µg). Representative gel image shown; actual purity may vary between each batch.

Gene Name : GFUS GDP-L-fucose synthase [ Homo sapiens (human) ]
Official Symbol : GFUS
Synonyms : GFUS; GDP-L-fucose synthase; FX; P35B; TSTA3; SDR4E1; GDP-L-fucose synthase; 3-5 epimerase/4-reductase; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; red cell NADP(H)-binding protein; short chain dehydrogenase/reductase family 4E, member 1; testis tissue sperm-binding protein Li 45a; tissue specific transplantation antigen 3; tissue specific transplantation antigen P35B
Gene ID : 7264
mRNA Refseq : NM_001317783
Protein Refseq : NP_001304712
MIM : 137020
UniProt ID : Q13630

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