Recombinant Human GLCE Protein (29-617 aa), His-tagged

• Cat.No.: GLCE-525H
• Product Overview: Recombinant Human GLCE Protein (29-617 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cancer. Protein Description: Partial.

Specification

• Description: Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 70.9 kDa
• Protein length: 29-617 aa
• AA Sequence: NKCSSDKAIQFPRRSSSGFRVDGFE KRAAASESNNYMNHVAKQQSEEAFP QEQQKAPPVVGGFNSNVGSKVLGLK YEEIDCLINDEHTIKGRREGNEVFL PFTWVEKYFDVYGKVVQYDGYDRFE FSHSYSKVYAQRAPYHPDGVFMSFE GYNVEVRDRVKCISGVEGVPLSTQW GPQGYFYPIQIAQYGLSHYSKNLTE KPPHIEVYETAEDRDKNKPNDWTVP KGCFMANVADKSRFTNVKQFIAPET SEGVSLQLGNTKDFIISFDLKFLTN GSVSVVLETTEKNQLFTIHYVSNAQ LIAFKERDIYYGIGPRTSWSTVTRD LVTDLRKGVGLSNTKAVKPTKIMPK KVVRLIAKGKGFLDNITISTTAHMA AFFAASDWLVRNQDEKGGWPIMVTR KLGEGFKSLEPGWYSAMAQGQAIST LVRAYLLTKDHIFLNSALRATAPYK FLSEQHGVKAVFMNKHDWYEEYPTT PSSFVLNGFMYSLIGLYDLKETAGE KLGKEARSLYERGMESLKAMLPLYD TGSGTIYDLRHFMLGIAPNLARWDY HTTHINQLQLLSTIDESPVFKEFVK RWKSYLKGSRAKHN
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: GLCE glucuronic acid epimerase [ Homo sapiens ]
• Official Symbol: GLCE
• Synonyms: GLCE; HSEPI; KIAA0836
• Gene ID: 26035
• mRNA Refseq: NM_015554
• Protein Refseq: NP_056369
• MIM: 612134
• UniProt ID: O94923