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Recombinant Human GLI2 Protein (412-641 aa), His-tagged

Cat.No. : GLI2-2038H
Product Overview : Recombinant Human GLI2 Protein (412-641 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial.
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  • Gene Information
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Description : Functions as transcription regulator in the hedgehog (Hh) pathway (PubMed:18455992). Functions as transcriptional activator (PubMed:9557682, PubMed:19878745, PubMed:24311597). May also function as transcriptional repressor (By similarity). Requires STK36 for full transcriptional activator activity. Required for normal embryonic development (PubMed:15994174, PubMed:20685856).
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 28.5 kDa
Protein length : 412-641 aa
AA Sequence : EQLADLKEDLDRDDCKQEAEVVIYE TNCHWEDCTKEYDTQEQLVHHINNE HIHGEKKEFVCRWQACTREQKPFKA QYMLVVHMRRHTGEKPHKCTFEGCS KAYSRLENLKTHLRSHTGEKPYVCE HEGCNKAFSNASDRAKHQNRTHSNE KPYICKIPGCTKRYTDPSSLRKHVK TVHGPDAHVTKKQRNDVHLRTPLLK ENGDSEAGTEPGGPESTEASSTSQA VEDCL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : GLI2 GLI family zinc finger 2 [ Homo sapiens ]
Official Symbol : GLI2
Synonyms : GLI2; GLI family zinc finger 2; HPE9; tax helper protein 1; tax helper protein 2; oncogene GLI2;
Gene ID : 2736
mRNA Refseq : NM_005270
Protein Refseq : NP_005261
MIM : 165230
UniProt ID : P10070

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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