Recombinant Human GLP1R Protein, hFc-tagged
Cat.No. : | GLP1R-583H |
Product Overview : | Recombinant Human GLP1R Protein(P43220)(Arg24-Tyr145), fused with C-terminal hFc tag, was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | Fc |
Protein Length : | 1-145 a.a. |
Tag : | C-hFc |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Bio-activity : | Immobilized Recombinant Human GLP-1R (C-Fc) at 5μg/ml (100 μl/well) can bind Anti-GLP-1R Antibody (Human IgG1). The ED50 of Anti-GLP-1R Antibody (Human IgG1) is 6.23 ng/ml. |
Molecular Mass : | 41.2 KDa |
Endotoxin : | < 1 EU/μg as determined by LAL test. |
Purity : | Greater than 90% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Reconstitution : | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name | GLP1R glucagon-like peptide 1 receptor [ Homo sapiens ] |
Official Symbol | GLP1R |
Synonyms | GLP1R; glucagon-like peptide 1 receptor; GLP-1R; GLP-1-R; GLP-1 receptor; MGC138331; |
Gene ID | 2740 |
mRNA Refseq | NM_002062 |
Protein Refseq | NP_002053 |
MIM | 138032 |
UniProt ID | P43220 |
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Loureirin B activates GLP‐1R and promotes insulin secretion in Ins‐1 cells
Journal: Journal of Cellular and Molecular Medicine PubMed ID: 33300675 Data: 2020/12/10
Authors: Yanting Ding, Sijing Xia, Bing Niu
Article Snippet:The recombinant protein GLP‐1R was obtained from Creative BioMart.. Loureirin B (LB) was purchased from National Institutes for Food and Drug Control.Loureirin B (LB) was purchased from National Institutes for Food and Drug Control.

Molecular docking results of LB and DPP‐IV, FFAR1, GK,

Molecular docking diagram of LB interaction with

SPR sensorgrams corresponding to different concentrations LB and
Cochinchinenin C, a potential nonpolypeptide anti-diabetic drug, targets a glucagon-like peptide-1 receptor
Journal: RSC Adv. Data: 2017/1/1
Authors: Yijie Sha, Yunfeng Shi, Qin Chen
Article Snippet:The recombinant protein GLP1 receptor was purchased from Creative BioMart and used without further purication, congured as 25 mM.. Cochinchinenin C was purchased from National Institutes for Food and Drug Control, and the stock 49016 | RSC Adv., 2017, 7, 49015–49023 solution of Cochinchinenin C (CC) was prepared in DMSO at 0.01 mol L 1.Cochinchinenin C was purchased from National Institutes for Food and Drug Control, and the stock 49016 | RSC Adv., 2017, 7, 49015–49023 solution of Cochinchinenin C (CC) was prepared in DMSO at 0.01 mol L 1.
Not For Human Consumption!
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