Recombinant Human GNA13, His-tagged

• Cat.No.: GNA13-13343H
• Product Overview: Recombinant Human GNA13 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-377a.a.
• Description: The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GNA13 guanine nucleotide binding protein (G protein), alpha 13 [ Homo sapiens ]
• Official Symbol: GNA13
• Synonyms: GNA13; guanine nucleotide binding protein (G protein), alpha 13; guanine nucleotide-binding protein subunit alpha-13; G13; MGC46138; g alpha-13; G-protein subunit alpha-13
• Gene ID: 10672
• mRNA Refseq: NM_006572
• Protein Refseq: NP_006563
• MIM: 604406
• UniProt ID: Q14344
• Chromosome Location: 17q24
• Pathway: CXCR4-mediated signaling events, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Hemostasis, organism-specific biosystem; LPA receptor mediated events, organism-specific biosystem
• Function: D5 dopamine receptor binding; G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity; guanyl nucleotide binding; metal ion binding; nucleotide binding; protein binding; signal transducer activity; type 1 angiotensin receptor binding