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Recombinant Human GNMT Protein, His-tagged

Cat.No.: GNMT-577H
Product Overview: Recombinant Human GNMT(Val2~Asp295) fused with His tag at N-terminal was expressed in E. coli.
Description: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644.
Source: E. coli
Species: Human
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 36.3kDa
Protein length: Val2~Asp295
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 96%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: GNMT glycine N-methyltransferase [ Homo sapiens ]
Official Symbol: GNMT
Synonyms: GNMT; glycine N-methyltransferase;
Gene ID: 27232
mRNA Refseq: NM_018960
Protein Refseq: NP_061833
MIM: 606628
UniProt ID: Q14749

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