Recombinant Human GON7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human GON7 Protein, Myc/DDK-tagged, C13 and N15-labeled

GON7 Related Products

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Cat.No. : GON7-501H
Product Overview : C14orf142 MS Standard C13 and N15-labeled recombinant protein (NP_115879) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit OSGEP in the complex.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 10.9 kDa
AA Sequence : MELLGEYVGQ EGKPQKLRVS CEAPGDGDPF QGLLSGVAQM KDMVTELFDP LVQGEVQHRV AAAPDEDLDG DDEDDAEDEN NIDNRTNFDG PSAKRPKTPS TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GON7 GON7 subunit of KEOPS complex [ Homo sapiens (human) ]
Official Symbol : GON7
Synonyms : GON7; GON7 subunit of KEOPS complex; PNAS-127; C14orf142; EKC/KEOPS complex subunit GON7; GON7, KEOPS complex subunit homolog; uncharacterized protein C14orf142
Gene ID : 84520
mRNA Refseq : NM_032490
Protein Refseq : NP_115879
MIM : 617436
UniProt ID : Q9BXV9

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