Recombinant Human GPI Protein, GST-tagged

• Cat.No.: GPI-5156H
• Product Overview: Human GPI full-length ORF ( AAH04982, 1 a.a. - 558 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 86.9 kDa
• AA Sequence: MAALTRDPQFQKLQQWYREHRSELN LRRLFDANKDRFNHFSLTLNTNHGH ILVDYSKNLVTEDVMRMLVDLAKSR GVEAARERMFNGEKINYTEGRAVLH VALRNRSNTPILVDGKDVMPEVNKV LDKMKSFCQRVRSGDWKGYTGKTIT DVINIGIGGSDLGPLMVTEALKPYS SGGPRVWYVSNIDGTHIAKTLAQLN PESSLFIIASKTFTTQETITNAETA KEWFLQAAKDPSAVAKHFVALSTNT TKVKEFGIDPQNMFEFWDWVGGRYS LWSAIGLSIALHVGFDNFEQLLSGA HWMDQHFRTTPLEKNAPVLLALLGI WYINCFGCETHAMLPYDQYLHRFAA YFQQGDMESNGKYITKSGTRVDHQT GPIVWGEPGTNGQHAFYQLIHQGTK MIPCDFLIPVQTQHPIRKGLHHKIL LANFLAQTEALMRGKSTEEARKELQ AAGKSPEDLERLLPHKVFEGNRPTN SIVFTKLTPFMLGALVAMYEHKIFV QGIIWDINSFDQWGVELGKQLAKKI EPELDGSAQVTSHDASTNGLINFIK QQREARVQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GPI glucose-6-phosphate isomerase [ Homo sapiens ]
• Official Symbol: GPI
• Synonyms: GPI; glucose-6-phosphate isomerase; glucose phosphate isomerase; AMF; NLK; neuroleukin; oxoisomerase; sperm antigen 36; sperm antigen-36; phosphohexomutase; phosphosaccharomutase; phosphohexose isomerase; phosphoglucose isomerase; autocrine motility factor; hexosephosphate isomerase; hexose monophosphate isomerase; PGI; PHI; GNPI; SA36; SA-36; DKFZp686C13233
• Gene ID: 2821
• mRNA Refseq: NM_000175
• Protein Refseq: NP_000166
• MIM: 172400
• UniProt ID: P06744