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Recombinant Human GPLD1 Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : GPLD1-434H
Product Overview : GPLD1 MS Standard C13 and N15-labeled recombinant protein (NP_001494) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 92.35 kDa
AA Sequence : MSAFRLWPGLLIMLGSLCHRGSPCG LSTHVEIGHRALEFLQLHNGRVNYR ELLLEHQDAYQAGIVFPDCFYPSIC KGGKFHDVSESTHWTPFLNASVHYI RENYPLPWEKDTEKLVAFLFGITSH MAADVSWHSLGLEQGFLRTMGAIDF HGSYSEAHSAGDFGGDVLSQFEFNF NYLARRWYVPVKDLLGIYEKLYGRK VITENVIVDCSHIQFLEMYGEMLAV SKLYPTYSTKSPFLVEQFQEYFLGG LDDMAFWSTNIYHLTSFMLENGTSD CNLPENPLFIACGGQQNHTQGSKMQ KNDFHRNLTTSLTESVDRNINYTER GVFFSVNSWTPDSMSFIYKALERNI RTMFIGGSQLSQKHVSSPLASYFLS FPYARLGWAMTSADLNQDGHGDLVV GAPGYSRPGHIHIGRVYLIYGNDLG LPPVDLDLDKEAHRILEGFQPSGRF GSALAVLDFNVDGVPDLAVGAPSVG SEQLTYKGAVYVYFGSKQGGMSSSP NITISCQDIYCNLGWTLLAADVNGD SEPDLVIGSPFAPGGGKQKGIVAAF YSGPSLSDKEKLNVEAANWTVRGEE DFSWFGYSLHGVTVDNRTLLLVGSP TWKNASRLGHLLHIRDEKKSLGRVY GYFPPNGQSWFTISGDKAMGKLGTS LSSGHVLMNGTLKQVLLVGAPTYDD VSKVAFLTVTLHQGGATRMYALISD AQPLLLSTFSGDRRFSRFGGVLHLS DLDDDGLDEIIMAAPLRIADVTSGL IGGEDGRVYVYNGKETTLGDMTGKC KSWITPCPEEKAQYVLISPEASSRF GSSLITVRSKAKNQVVIAAGRSSLG ARLSGALHVYSLGSDTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : GPLD1 glycosylphosphatidylinositol specific phospholipase D1 [ Homo sapiens (human) ]
Official Symbol : GPLD1
Synonyms : GPLD1; glycosylphosphatidylinositol specific phospholipase D1; phosphatidylinositol-glycan-specific phospholipase D; GPI-PLD; PI-G PLD; GPI-specific phospholipase D; glycoprotein phospholipase D; phospholipase D, phosphatidylinositol-glycan-specific; glycosylphosphatidylinositol specific phospholipase D1, isoform 2; GPIPLD; PIGPLD; GPIPLDM; PIGPLD1; MGC22590;
Gene ID : 2822
mRNA Refseq : NM_001503
Protein Refseq : NP_001494
MIM : 602515
UniProt ID : P80108

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does GPLD1 interact with other enzymes in carbohydrate and lipid metabolism? 12/10/2022

GPLD1 works with other metabolic enzymes, coordinating carbohydrate and lipid metabolism.

What potential therapeutic applications arise from targeting GPLD1 in metabolic diseases? 02/27/2022

Targeting GPLD1 offers potential in treating metabolic disorders by regulating liver metabolism.

What role does GPLD1 play in lipid metabolism? 02/28/2021

GPLD1 is also involved in lipid metabolism, affecting fat processing and storage.

What is the impact of altered GPLD1 activity on metabolic disorders? 10/22/2020

Altered GPLD1 activity is linked to various metabolic disorders, including diabetes and liver diseases.

What is the primary role of GPLD1 in liver function? 10/27/2018

GPLD1, a glycosylphosphatidylinositol-specific phospholipase, is involved in modulating liver metabolism and function.

How do genetic variations in GPLD1 affect liver health? 08/26/2018

Genetic variations in GPLD1 can lead to altered metabolic processing, impacting liver health and function.

How does GPLD1 contribute to glycogen metabolism? 07/17/2017

It plays a role in glycogen metabolism, impacting glucose regulation in the liver.

Customer Reviews (3)

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12/29/2022

    Swift and accurate service, essential for research progress.

    10/20/2022

      Invaluable support for insights, a research necessity.

      09/23/2021

        Trustworthy results, accelerates our research success.

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