Recombinant Human GPR77 Protein

• Cat.No.: GPR77-5263H
• Product Overview: Human GPR77 full-length ORF (NP_060955.1) recombinant protein without tag.

Specification

• Description: The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 36.1 kDa
• AA Sequence: MGNDSVSYEYGDYSDLSDRPVDCLD GACLAIDPLRVAPLPLYAAIFLVGV PGNAMVAWVAGKVARRRVGATWLLH LAVADLLCCLSLPILAVPIARGGHW PYGAVGCRALPSIILLTMYASVLLL AALSADLCFLALGPAWWSTVQRACG VQVACGAAWTLALLLTVPSAIYRRL HQEHFPARLQCVVDYGGSSSTENAV TAIRFLFGFLGPLVAVASCHSALLC WAARRCRPLGTAIVVGFFVCWAPYH LLGLVLTVAAPNSALLARALRAEPL IVGLALAHSCLNPMLFLYFGRAQLR RSLPAACHWALRESQGQDESVDSKK STSHDLVSEMEV
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: GPR77 G protein-coupled receptor 77 [ Homo sapiens ]
• Official Symbol: GPR77
• Synonyms: GPR77; G protein-coupled receptor 77; C5a anaphylatoxin chemotactic receptor C5L2; C5L2; G-protein coupled receptor 77; G protein-coupled receptor C5L2; GPF77
• Gene ID: 27202
• mRNA Refseq: NM_018485
• Protein Refseq: NP_060955
• MIM: 609949
• UniProt ID: Q9P296