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Recombinant Human GRID2 Protein, GST-tagged

Cat.No. : GRID2-5335H
Product Overview : Human GRID2 partial ORF ( NP_001501, 908 a.a. - 1007 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named lurcher, in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.74 kDa
AA Sequence : DTLPTRQALEQISDFRNTHITTTTF IPEQIQTLSRTLSAKAASGFTFGNV PEHRTGPFRHRAPNGGFFRSPIKTM SSIPYQPTPTLGLNLGNDPDRGTSI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GRID2 glutamate receptor, ionotropic, delta 2 [ Homo sapiens ]
Official Symbol : GRID2
Synonyms : GRID2; glutamate receptor, ionotropic, delta 2; glutamate receptor delta-2 subunit; GluD2; GluR delta 2; GluR-delta-2; gluR delta-2 subunit; MGC117022; MGC117023; MGC117024;
Gene ID : 2895
mRNA Refseq : NM_001510
Protein Refseq : NP_001501
MIM : 602368
UniProt ID : O43424

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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