Recombinant Human GRM5 Protein (P569-K678, E579A, N667Y, I669A, G675M, K679-A836, T742A, S753A), Flag, His tagged

• Cat.No.: GRM5-0501H
• Product Overview: Recombinant Human GRM5(P569-K678) (E579A, N667Y, I669A, G675M)-T4L-GRM5(K679-A836) (T742A, S753A)-10His Protein was expressed in Insect cell.

Specification

• Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
• Source: Insect cell
• Species: Human
• Tag: Flag,His
• Form: Liquid
• Protein Length: P569-K678, E579A, N667Y, I669A, G675M, K679-A836, T742A, S753A
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: GRM5 glutamate receptor, metabotropic 5 [ Homo sapiens (human) ]
• Official Symbol: GRM5
• Synonyms: GRM5; glutamate receptor, metabotropic 5; metabotropic glutamate receptor 5; GPRC1E; mGlu5; MGLUR5; metabotropic glutamate receptor 5 variant F; metabotropic glutamate receptor 5 variant G; metabotropic glutamate receptor 5 variant H
• Gene ID: 2915
• mRNA Refseq: NM_000842
• Protein Refseq: NP_000833
• MIM: 604102
• UniProt ID: P41594