Recombinant Human Growth Arrest And DNA-Damage-Inducible, Gamma Interacting Protein 1, His-tagged

• Cat.No.: GADD45GIP1-1280H
• Product Overview: Recombinant human GADD45GIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: GADD45GIP1, also known as CRIF1, is a nuclear protein that plays a role in apoptosis control. This protein is expressed in a variety of tissues, including heart, thyroid, trachea, kidney, ovary, pancreas, testis and stomach. It functions as a negative regulator of G1 to S phase cell cycle production, specifically by working with GADD45 proteins to inhibit the activity of cyclin-dependent kinases.
• Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 40% glycerol 2mM DTT, 0.2M NaCl.
• Molecular Weight: 22.6 kDa (196aa), confirmed by MALDI-TOF
• Purity: > 90 % by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by Bradford)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MPRWQLGPRY AAKQFARYGA ASGVVPGSLW PSPEQLRELE AEEREWYPSL ATMQESLRVK QLAEEQKRRE REQHIAECMA KMPQMIVNWQ QQQRENWEKA QADKERRARL QAEAQELLGY QVDPRSARFQ ELLQDLEKKE RKRLKEEKQK RKKEARAAAL AAAVAQDPAA SGAPSS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 [ Homo sapiens ]
• Official Symbol: GADD45GIP1
• Synonyms: GADD45GIP1; CKBBP2; CKII beta binding protein 2; CKII beta-associating protein; CR6 interacting factor 1; CR6-interacting factor 1; CRIF1; Growth arrest and DNA damage-inducible proteins-interacting protein 1; growth arrest and DNA damage-inducible proteins-interacting protein 1; growth arrest and DNA-damage-inducible, gamma interacting protein 1; MGC4667; MGC4758; p53-responsive gene 6 protein; papillomavirus L2 interacting nuclear protein 1; papillomavirus L2-interacting nuclear protein 1; PLINP1; PLINP-1; Plinp1; PRG6
• Gene ID: 90480
• mRNA Refseq: NM_052850
• Protein Refseq: NP_443082
• MIM: 605162
• UniProt ID: Q8TAE8
• Chromosome Location: 19p13.2
• Function: protein binding