Recombinant Human GSK3B Protein, DDK-tagged

• Cat.No.: GSK3B-120H
• Product Overview: Recombinant Human GSK3B fused with DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: Insect cells
• Species: Human
• Tag: DDK
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
• Molecular Mass: 47.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GSK3B glycogen synthase kinase 3 beta [ Homo sapiens ]
• Official Symbol: GSK3B
• Synonyms: GSK3B; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 beta; GSK-3 beta; GSK3beta isoform; serine/threonine-protein kinase GSK3B
• Gene ID: 2932
• mRNA Refseq: NM_002093
• Protein Refseq: NP_002084
• MIM: 605004
• UniProt ID: P49841