Recombinant Human GTF2F2, His-tagged

• Cat.No.: GTF2F2-13594H
• Product Overview: Recombinant Human GTF2F2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-249a.a.
• Description: This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity.
• Source: E.coli
• Species: Human
• Tag: His
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa [ Homo sapiens ]
• Official Symbol: GTF2F2
• Synonyms: GTF2F2; general transcription factor IIF, polypeptide 2, 30kDa; general transcription factor IIF, polypeptide 1 (74kD subunit); general transcription factor IIF subunit 2; BTF4; RAP30; TFIIF; TFIIF-beta; ATP-dependent helicase GTF2F2; transcription initiation factor RAP30; general transcription factor IIF 30 kDa subunit; transcription initiation factor IIF subunit beta; TF2F2
• Gene ID: 2963
• mRNA Refseq: NM_004128
• Protein Refseq: NP_004119
• MIM: 189969
• UniProt ID: P13984
• Chromosome Location: 13q14
• Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Disease, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem
• Function: ATP binding; ATP-dependent helicase activity; DNA binding; helicase activity; hydrolase activity; nucleotide binding; protein binding