Recombinant Human GTPBP3 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human GTPBP3 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : GTPBP3-299H
Product Overview : GTPBP3 MS Standard C13 and N15-labeled recombinant protein (NP_116009) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 52 kDa
AA Sequence : MWRGLWTLAA QAARGPRRLC TRRSSGAPAP GSGATIFALS SGQGRCGIAV IRTSGPASGH ALRILTAPRD LPLARHASLR LLSDPRSGEP LDRALVLWFP GPQSFTGEDC VEFHVHGGPA VVSGVLQALG SVPGLRPAEA GEFTRRAFAN GKLNLTEVEG LADLIHAETE AQRRQALRQL DGELGHLCRG WAETLTKALA HVEAYIDFGE DDNLEEGVLE QADIEVRALQ VALGAHLRDA RRGQRLRSGV HVVVTGPPNA GKSSLVNLLS RKPVSIVSPE PGTTRDVLET PVDLAGFPVL LSDTAGLREG VGPVEQEGVR RARERLEQAD LILAMLDASD LASPSSCNFL ATVVASVGAQ SPSDSSQHLL LVLNKSDLLS PEGPGPGPDL PPHLLLSCLT GEGLDGLLEA LRKELAAVCG DPSTDPPLLT RARHQHHLQG CLDALGHYKQ SKDLALAAEA LRVARGHLTR LTGGGGTEEI LDIIFQDFCV GKTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : GTPBP3 GTP binding protein 3 (mitochondrial) [ Homo sapiens (human) ]
Official Symbol : GTPBP3
Synonyms : GTPBP3; GTP binding protein 3 (mitochondrial); tRNA modification GTPase GTPBP3, mitochondrial; FLJ14700; GTPBG3; MSS1; MTGP1; THDF1; mitochondrial GTP-binding protein 1; FLJ17836;
Gene ID : 84705
mRNA Refseq : NM_032620
Protein Refseq : NP_116009
MIM : 608536
UniProt ID : Q969Y2

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