Recombinant Human Guanine Nucleotide-Binding Protein Subunit Beta-2-Like 1, His-tagged
Cat.No. : | GNB2L1-1375H |
Product Overview : | Recombinant humanGNB2L1 protein, fused to His-tag at N-terminus, wasexpressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Cat. No. : | GNB2L1-1375H |
Description : | GNB2L1 wasoriginally identified as an anchoring protein for protein kinase C beta(PKCbeta), which it stabilises in the active state and anchors to membranesor functional sites. However, evidence has accumulated to support a centralrole of GNB2L1 in critical biological responses. |
Form : | Liquid. In 20 mMTris-HCl buffer (pH 8.0) containing 5 mM DTT, 50% glycerol, 0.2M NaCl. |
Molecular Weight : | 37.2 kDa (337 aa)confirmed by MALDI-TOF. |
Purity : | > 90%by SDS-PAGE |
Concentration : | 0.25 mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDETNYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQIVSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIGHTGYLNTVTV SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA ATGPSIKIWDLEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA GYTDNLVRVW QVTIGTR |
Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | CXCR4-mediatedsignaling events; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha;IGF1 pathway; IL-2 Signaling Pathway; IL-3 Signaling Pathway; Measles;Regulation of Androgen receptor activity; Syndecan-2-mediated signalingevents; TNF receptor signaling pathway; TNF-alpha/NF-kB Signaling Pathway |
Gene Name : | GNB2L1 guanine nucleotidebinding protein (G protein), beta polypeptide 2-like 1 [ Homo sapiens] |
Official Symbol : | GNB2L1 |
Synonyms : | GNB2L1;guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1;guanine nucleotide-binding protein subunit beta-2-like 1; OTTHUMP00000223704;OTTHUMP00000223870; OTTHUMP00000223891; OTTHUMP00000223893;OTTHUMP00000223900; OTTHUMP00000223902; OTTHUMP00000223930; OTTHUMP00000223931;lung cancer oncogene 7; proliferation-inducing gene 21; Receptor forActivated C Kinase 1; human lung cancer oncogene 7 protein; receptor ofactivated protein kinase C 1; cell proliferation-inducing gene 21 protein;guanine nucleotide-binding protein subunit beta-like protein 12.3; proteinhomologous to chicken B complex protein, guanine nucleotide binding |
Gene ID : | 10399 |
mRNA Refseq : | NM_006098 |
Protein Refseq : | NP_006089 |
MIM : | 176981 |
UniProt ID : | P63244 |
Chromosome Location : | 5q35.3 |
Function : | SH2domain binding; ion channel inhibitor activity; protein binding; proteinkinase C binding; protein phosphatase binding; protein tyrosine kinaseinhibitor activity; receptor binding; receptor tyrosine kinase binding |
Products Types
◆ Recombinant Protein | ||
GNB2L1-3767M | Recombinant Mouse GNB2L1 Protein, His (Fc)-Avi-tagged | +Inquiry |
GNB2L1-9012Z | Recombinant Zebrafish GNB2L1 | +Inquiry |
GNB2L1-7028M | Recombinant Mouse GNB2L1 Protein | +Inquiry |
GNB2L1-2655H | Recombinant Human GNB2L1 protein, His-tagged | +Inquiry |
GNB2L1-30327TH | Recombinant Human GNB2L1, His-tagged | +Inquiry |
◆ Lysates | ||
GNB2L1-5862HCL | Recombinant Human GNB2L1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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