Recombinant Human GUCY1B1 Protein (His408-Asp619), N-His tagged

• Cat.No.: GUCY1B1-2562H
• Product Overview: Recombinant human GUCY1B1 (His408-Asp619) protein fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: His408-Asp619
• Description: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 26.07 kDa
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 [ Homo sapiens (human) ]
• Official Symbol: GUCY1B1
• Synonyms: GUCY1B1; guanylate cyclase 1 soluble subunit beta 1; GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B3; GC-S-beta-1; guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; guanylate cyclase 1, soluble, beta 3; guanylate cyclase soluble subunit beta-3; soluble guanylate cyclase small subunit; EC 4.6.1.2
• Gene ID: 2983
• mRNA Refseq: NM_000857
• Protein Refseq: NP_000848
• MIM: 139397
• UniProt ID: Q02153