Recombinant Human GZMK Protein, His-tagged

• Cat.No.: GZMK-7765H
• Product Overview: Recombinant Human Granzyme K (GZMK), His-tagged. Expressed in E. coli. GZMK is a trypsin-like serine protease from the cytoplasmic granules of cytotoxic lymphocytes (CTL and NK cells). Detectable by anti-His antibody in WB.

Specification

• Species: Human
• Source: E. coli
• Tag: His
• Protein Length: 19-247 aa
• Description: Granzyme K (GZMK) is a member of the granzyme family of serine proteases found in the granules of cytotoxic T cells and NK cells. GZMK has been shown to play a role in the GZMK pathway of complement activation, leading to phagocytosis and breakdown of target cells. It is a trypsin-like serine protease that cleaves after basic residues.
• Form: Lyophilized powder
• Molecular Mass: 28 kDa
• Endotoxin: < 1.0 EU/ug
• Purity: > 90%
• Storage: -20°C ~ -80°C
• EC: 3.4.21.-

Gene Information

• Gene Name: GZMK
• Official Symbol: GZMK
• Synonyms: GrK; TRYP2; NK-Tryp-2; NK-tryptase-2; fragmentin-3; granzyme 3; tryptase II
• Gene ID: 3003
• mRNA Refseq: NM_002104.3
• Protein Refseq: NP_002095.1
• MIM: 600784
• UniProt ID: P49863