Recombinant Human HBD, GST-tagged

• Cat.No.: HBD-13680H
• Product Overview: Recombinant Human HBD protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-147a.a.
• Description: The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5-epsilon--Ggamma--Agamma--delta--beta-3. Mutations in the delta-globin gene are associated with beta-thalassemia.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HBD hemoglobin, delta [ Homo sapiens ]
• Official Symbol: HBD
• Synonyms: hemoglobin, delta; 4829; Ensembl:ENSG00000223609; hemoglobin subunit delta;delta globin;delta-globin chain;hemoglobin delta chain
• Gene ID: 3045
• mRNA Refseq: NM_000519.3
• Protein Refseq: NP_000510.1
• MIM: 142000
• UniProt ID: A0N071
• Chromosome Location: 11p15.5
• Pathway: Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Metabolism, organism-specific biosystem; O2/CO2 exchange in erythrocytes, organism-specific biosystem; Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes, organism-specific biosystem; Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes, organism-specific biosystem
• Function: heme binding; iron ion binding; oxygen binding; oxygen transporter activity