Recombinant Human HCFC1 Protein, GST-tagged

• Cat.No.: HCFC1-4617H
• Product Overview: Human HCFC1 full-length ORF ( AAH63435.1, 1 a.a. - 428 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 73.6 kDa
• AA Sequence: MASAVSPANLPAVLLQPRWKRVVGW SGPVPRPRHGHRAVAIKELIVVFGG GNEGIVDELHVYNTATNQWFIPAVR GDIPPGCAAYGFVCDGTRLLVFGGM VEYGKYSNDLYELQASRWEWKRLKA KTPKNGPPPCPRLGHSFSLVGNKCY LFGGLANDSEDPKNNIPRYLNDLYI LELRPGSGVVAWDIPITYGVLPPPR ESHTAVVYTEKDNKKSKLVIYGGMS GCRLGDLWTLDIDTLTWNKPSLSGV APLPRSLHSATTIGNKMYVFGGWVP LVMDDVKVATHEKEWKCTNTLACLN LDTMAWETILMDTLEDNIPRARAGH CAVAINTRLYIWSGRDGYRKAWNNQ VCCKDLWYLETEKPPPPARVQLVRA NTNSLEVSWGAVATADSYLLQLQKY DIPATAATATSPTPNPVPSVPANPP KSL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HCFC1 host cell factor C1 (VP16-accessory protein) [ Homo sapiens ]
• Official Symbol: HCFC1
• Synonyms: HCFC1; host cell factor C1 (VP16-accessory protein); HFC1; host cell factor 1; CFF; HCF 1; HCF1; MGC70925; VCAF; HCF; C1 factor; VP16 accessory protein; HCF-1
• Gene ID: 3054
• mRNA Refseq: NM_005334
• Protein Refseq: NP_005325
• MIM: 300019
• UniProt ID: P51610