| Description : |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
99.5 kDa |
| AA Sequence : |
MDLRVGQRPPVEPPPEPTLLALQRP QRLHHHLFLAGLQQQRSVEPMRLSM DTPMPELQVGPQEQELRQLLHKDKS KRSAVASSVVKQKLAEVILKKQQAA LERTVHPNSPGIPYRTLEPLETEGA TRSMLSSFLPPVPSLPSDPPEHFPL RKTVSEPNLKLRYKPKKSLERRKNP LLRKESAPPSLRRRPAETLGDSSPS SSSTPASGCSSPNDSEHGPNPILGD SDRRTHPTLGPRGPILGSPHTPLFL PHGLEPEAGGTLPSRLQPILLLDPS GSHAPLLTVPGLGPLPFHFAQSLMT TERLSGSGLHWPLSRTRSEPLPPSA TAPPPPGPMQPRLEQLKTHVQVIKR SAKPSEKPRLRQIPSAEDLETDGGG PGQVVDDGLEHRELGHGQPEARGPA PLQQHPQVLLWEQQRLAGRLPRGST GDTVLLPLAQGGHRPLSRAQSSPAA PASLSAPEPASQARVLSSSETPART LPFTTGLIYDSVMLKHQCSCGDNSR HPEHAGRIQSIWSRLQERGLRSQCE CLRGRKASLEELQSVHSERHVLLYG TNPLSRLKLDNGKLAGLLAQRMFVM LPCGGVGVDTDTIWNELHSSNAARW AAGSVTDLAFKVASRELKNGFAVVR PPGHHADHSTAMGFCFFNSVAIACR QLQQQSKASKILIVDWDVHHGNGTQ QTFYQDPSVLYISLHRHDDGNFFPG SGAVDEVGAGSGEGFNVNVAWAGGL DPPMGDPEYLAAFRIVVMPIAREFS PDLVLVSAGFDAAEGHPAPLGGYHV SAKCFGYMTQQLMNLAGGAVVLALE GGHDLTAICDASEACVAALLGNRVD PLSEEGWKQKPNLNAIRSLEAVIRV HSKYWGCMQRLASCPDSWVPRVPGA DKEEVEAVTALASLSVGILAEDRPS EQLVEEEEPMNLTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
