Recombinant Human HDC Protein, GST-tagged

• Cat.No.: HDC-4654H
• Product Overview: Human HDC full-length ORF ( ADR83232.1, 1 a.a. - 662 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC; EC 4.1.1.22). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 72.9 kDa
• AA Sequence: MMEPEEYRERGREMVDYICQYLSTV RERRVMPDVQPGYLRAQLPESAPED PDSWDSIFGDIERIIMPGVVHWQSP HMHAYYPALTSWPSLLGDMLADAIN CLGFTWASSPACTELEMNVMDWLAK MLGLPEHFLHHHPSSQGGGVLQSTV SESTLIALLAARKNKILEMKTSEPD ADESCLNARLVAYASDQAHSSVEKA GLISLVKMKFLPVDDNFSLRGEALQ KAIEEDKQRGLVPVFVCATLGTTGV CAFDCLSELGPICAREGLWLHIDAA YAGTAFLCPEFRGFLKGIEYADSFT FNPSKWMMVHFDCTGFWVKDKYKLQ QTFSVNPIYLRHANSGVATDFMHWQ IPLSRRFRSVKLWFVIRSFGVKNLQ AHVRHGTEMAKYFESLVRNDPSFEI PAKRHLGLVVFRLKGPNCLTENVLK EIAKAGRLFLIPATIQDKLIIRFTV TSQFTTRDDILRDWNLIRDAATLIL SQHCTSQPSPRVGNLISQIRGARAW ACGTSLQSVSGAGDDPVQARKIIKQ PQRVGAGPMKRENGLHLETLLDPVD DCFSEEAPDATKHKLSSFLFSYLSV QTKKKTVRSLSCNSVPVSAQKPLPT EASVKNGGSSRVRIFSRFPEDMMML KKSAFKKLIKFYSVPSFPECSSQCG LQLPCCPLQAMV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HDC histidine decarboxylase [ Homo sapiens ]
• Official Symbol: HDC
• Synonyms: HDC; histidine decarboxylase; MGC163399
• Gene ID: 3067
• mRNA Refseq: NM_002112
• Protein Refseq: NP_002103
• MIM: 142704
• UniProt ID: P19113