Recombinant Human HEBP1, His-tagged

• Cat.No.: HEBP1-7070H
• Product Overview: Recombinant human HEBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: HEBP1 is an intracellular tetrapyrrole-binding protein. HEBP1 includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,30% glycerol, 1mM DTT
• Molecular Mass: 23.5 kDa (212aa)
• Protein length: 1-189aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLGMIKN SLFGSVETWP WQVLSKGDKE EVAYEERACE GGKFATVEVT DKPVDEALRE AMPKVAKYAGGTNDKGIGMG MTVPISFAVF PNEDGSLQKK LKVWFRIPNQ FQSDPPAPSD KSVKIEEREG ITVYSMQFGG YAKEADYVAQ ATRLRAALEG TATYRGDIYF CTGYDPPMKP YGRRNEIWLL KT
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: HEBP1 heme binding protein 1 [ Homo sapiens ]
• Official Symbol: HEBP1
• Synonyms: HEBP1; heme binding protein 1; heme-binding protein 1; HBP; HEBP; p22HBP
• Gene ID: 50865
• mRNA Refseq: NM_015987
• Protein Refseq: NP_057071
• MIM: 605826
• UniProt ID: Q9NRV9
• Chromosome Location: 12p13.2
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Formyl peptide receptors bind formyl peptides and many other ligands, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem
• Function: binding; heme binding