Recombinant Human HEPACAM2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HEPACAM2-1107H
• Product Overview: HEPACAM2 MS Standard C13 and N15-labeled recombinant protein (NP_001034461) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.2 kDa
• AA Sequence: MGQDAFMEPFGDTLGVFQCKIYLLL FGACSGLKVTVPSHTVHGVRGQALY LPVHYGFHTPASDIQIIWLFERPHT MPKYLLGSVNKSVVPDLEYQHKFTM MPPNASLLINPLQFPDEGNYIVKVN IQGNGTLSASQKIQVTVDDPVTKPV VQIHPPSGAVEYVGNMTLTCHVEGG TRLAYQWLKNGRPVHTSSTYSFSPQ NNTLHIAPVTKEDIGNYSCLVRNPV SEMESDIIMPIIYYGPYGLQVNSDK GLKVGEVFTVDLGEAILFDCSADSH PPNTYSWIRRTDNTTYIIKHGPRLE VASEKVAQKTMDYVCCAYNNITGRQ DETHFTVIITSVGLEKLAQKGKSLS PLASITGISLFLIISMCLLFLWKKY QPYKVIKQKLEGRPETEYRKAQTFS GHEDALDDFGIYEFVAFPDVSGVSR IPSRSVPASDCVSGQDLHSTVYEVI QHIPAQQQDHPETRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HEPACAM2 HEPACAM family member 2 [ Homo sapiens (human) ]
• Official Symbol: HEPACAM2
• Synonyms: HEPACAM2; HEPACAM family member 2; FLJ38683; mitotic kinetics regulator; MIKI
• Gene ID: 253012
• mRNA Refseq: NM_001039372
• Protein Refseq: NP_001034461
• MIM: 614133
• UniProt ID: A8MVW5