Recombinant Human HEXB Protein, GST-tagged
Cat.No. : | HEXB-4711H |
Product Overview : | Human HEXB full-length ORF ( NP_000512.1, 1 a.a. - 556 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 89.5 kDa |
AA Sequence : | MELCGLGLPRPPMLLALLLATLLAA MLALLTQVALVVQVAEAARAPSVSA KPGPALWPLPLSVKMTPNLLHLAPE NFYISHSPNSTAGPSCTLLEEAFRR YHGYIFGFYKWHHEPAEFQAKTQVQ QLLVSITLQSECDAFPNISSDESYT LLVKEPVAVLKANRVWGALRGLETF SQLVYQDSYGTFTINESTIIDSPRF SHRGILIDTSRHYLPVKIILKTLDA MAFNKFNVLHWHIVDDQSFPYQSIT FPELSNKGSYSLSHVYTPNDVRMVI EYARLRGIRVLPEFDTPGHTLSWGK GQKDLLTPCYSRQNKLDSFGPINPT LNTTYSFLTTFFKEISEVFPDQFIH LGGDEVEFKCWESNPKIQDFMRQKG FGTDFKKLESFYIQKVLDIIATINK GSIVWQEVFDDKAKLAPGTIVEVWK DSAYPEELSRVTASGFPVILSAPWY LDLISYGQDWRKYYKVEPLDFGGTQ KQKQLFIGGEACLWGEYVDATNLTP RLWPRASAVGERLWSSKDVRDMDDA YDRLTRHRCRMVERGIAAQPLYAGY CNHENM |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HEXB hexosaminidase B (beta polypeptide) [ Homo sapiens ] |
Official Symbol : | HEXB |
Synonyms : | HEXB; hexosaminidase B (beta polypeptide); beta-hexosaminidase subunit beta; HCC-7; hexosaminidase subunit B; beta-N-acetylhexosaminidase subunit beta; cervical cancer proto-oncogene 7 protein; N-acetyl-beta-glucosaminidase subunit beta; ENC-1AS; |
Gene ID : | 3074 |
mRNA Refseq : | NM_000521 |
Protein Refseq : | NP_000512 |
MIM : | 606873 |
UniProt ID : | P07686 |
Products Types
◆ Recombinant Protein | ||
HEXB-2489R | Recombinant Rat HEXB Protein, His (Fc)-Avi-tagged | +Inquiry |
HEXB-4139M | Recombinant Mouse HEXB Protein, His (Fc)-Avi-tagged | +Inquiry |
HEXB-1891R | Recombinant Rhesus Macaque HEXB Protein, His (Fc)-Avi-tagged | +Inquiry |
Hexb-1117M | Recombinant Mouse Hexb Protein, MYC/DDK-tagged | +Inquiry |
HEXB-1090H | Recombinant Human HEXB Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
HEXB-756HCL | Recombinant Human HEXB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket