Recombinant Human HIST1H4A Protein, His-tagged

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Recombinant Human HIST1H4A Protein, His-tagged

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Cat.No. : HIST1H4A-437H
Product Overview : Recombinant Human HIST1H4A fused with His tag at N-terminal was expressed in E. coli.
Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 11.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : HIST1H4A histone cluster 1 H4 family member a [ Homo sapiens ]
Official Symbol : HIST1H4A
Synonyms : H4FA
Gene ID : 8359
mRNA Refseq : NM_003538
Protein Refseq : NP_003529
UniProt ID : P62805

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