Recombinant Human HIST2H3A Protein, GST-tagged

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Recombinant Human HIST2H3A Protein, GST-tagged

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Cat.No. : HIST2H3A-4812H
Product Overview : Human HIST2H3A full-length ORF ( NP_001005464.1, 1 a.a. - 136 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 41.8 kDa
AA Sequence : MARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : HIST2H3A histone cluster 2, H3a [ Homo sapiens ]
Official Symbol : HIST2H3A
Synonyms : HIST2H3A; histone cluster 2, H3a; histone 2, H3a; histone H3.2; H3/n; H3/o; histone H3/m; histone H3/o; HIST2H3C; HIST2H3D;
Gene ID : 333932
mRNA Refseq : NM_001005464
Protein Refseq : NP_001005464
UniProt ID : Q71DI3

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