| Description : |
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
102.3 kDa |
| AA Sequence : |
MIAAQLLAYYFTELKDDQVKKIDKY LYAMRLSDETLIDIMTRFRKEMKNG LSRDFNPTATVKMLPTFVRSIPDGS EKGDFIALDLGGSSFRILRVQVNHE KNQNVHMESEVYDTPENIVHGSGSQ LFDHVAECLGDFMEKRKIKDKKLPV GFTFSFPCQQSKIDEAILITWTKRF KASGVEGADVVKLLNKAIKKRGDYD ANIVAVVNDTVGTMMTCGYDDQHCE VGLIIGTGTNACYMEELRHIDLVEG DEGRMCINTEWGAFGDDGSLEDIRT EFDREIDRGSLNPGKQLFEKMVSGM YLGELVRLILVKMAKEGLLFEGRIT PELLTRGKFNTSDVSAIEKNKEGLH NAKEILTRLGVEPSDDDCVSVQHVC TIVSFRSANLVAATLGAILNRLRDN KGTPRLRTTVGVDGSLYKTHPQYSR RFHKTLRRLVPDSDVRFLLSESGSG KGAAMVTAVAYRLAEQHRQIEETLA HFHLTKDMLLEVKKRMRAEMELGLR KQTHNNAVVKMLPSFVRRTPDGTEN GDFLALDLGGTNFRVLLVKIRSGKK RTVEMHNKIYAIPIEIMQGTGEELF DHIVSCISDFLDYMGIKGPRMPLGF TFSFPCQQTSLDAGILITWTKGFKA TDCVGHDVVTLLRDAIKRREEFDLD VVAVVNDTVGTMMTCAYEEPTCEVG LIVGTGSNACYMEEMKNVEMVEGDQ GQMCINMEWGAFGDNGCLDDIRTHY DRLVDEYSLNAGKQRYEKMISGMYL GEIVRNILIDFTKKGFLFRGQISET LKTRGIFETKFLSQIESDRLALLQV RAILQQLGLNSTCDDSILVKTVCGV VSRRAAQLCGAGMAAVVDKIRENRG LDRLNVTVGVDGTLYKLHPHFSRIM HQTVKELSPKCNVSFLLSEDGSGKG AALITAVGVRLRTEASSTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
