| Description : |
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
102.2 kDa |
| AA Sequence : |
MIASHLLAYFFTELNHDQVQKVDQY LYHMRLSDETLLEISKRFRKEMEKG LGATTHPTAAVKMLPTFVRSTPDGT EHGEFLALDLGGTNFRVLWVKVTDN GLQKVEMENQIYAIPEDIMRGSGTQ LFDHIAECLANFMDKLQIKDKKLPL GFTFSFPCHQTKLDESFLVSWTKGF KSSGVEGRDVVALIRKAIQRRGDFD IDIVAVVNDTVGTMMTCGYDDHNCE IGLIVGTGSNACYMEEMRHIDMVEG DEGRMCINMEWGAFGDDGSLNDIRT EFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLS PELLNTGRFETKDISDIEGEKDGIR KAREVLMRLGLDPTQEDCVATHRIC QIVSTRSASLCAATLAAVLQRIKEN KGEERLRSTIGVDGSVYKKHPHFAK RLHKTVRRLVPGCDVRFLRSEDGSG KGAAMVTAVAYRLADQHRARQKTLE HLQLSHDQLLEVKRRMKVEMERGLS KETHASAPVKMLPTYVCATPDGTEK GDFLALDLGGTNFRVLLVRVRNGKW GGVEMHNKIYAIPQEVMHGTGDELF DHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKA SGCEGEDVVTLLKEAIHRREEFDLD VVAVVNDTVGTMMTCGFEDPHCEVG LIVGTGSNACYMEEMRNVELVEGEE GRMCVNMEWGAFGDNGCLDDFRTEF DVAVDELSLNPGKQRFEKMISGMYL GEIVRNILIDFTKRGLLFRGRISER LKTRGIFETKFLSQIESDCLALLQV RAILQHLGLESTCDDSIIVKEVCTV VARRAAQLCGAGMAAVVDRIRENRG LDALKVTVGVDGTLYKLHPHFAKVM HETVKDLAPKCDVSFLQSEDGSGKG AALITAVACRIREAGQRTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
