Recombinant Human HLA-DOB Protein, GST-tagged
Cat.No. : | HLA-DOB-4839H |
Product Overview : | Human HLA-DOB partial ORF ( NP_002111, 27 a.a. - 116 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 35.64 kDa |
AA Sequence : | TDSPEDFVIQAKADCYFTNGTEKVQ FVVRFIFNLEEYVRFDSDVGMFVAL TKLGQPDAEQWNSRLDLLERSRQAV DGVCRHNYRLGAPFT |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HLA-DOB major histocompatibility complex, class II, DO beta [ Homo sapiens ] |
Official Symbol : | HLA-DOB |
Synonyms : | HLA-DOB; major histocompatibility complex, class II, DO beta; HLA class II histocompatibility antigen, DO beta chain; MHC class II antigen DOB; DOB; FLJ57033; |
Gene ID : | 3112 |
mRNA Refseq : | NM_002120 |
Protein Refseq : | NP_002111 |
MIM : | 600629 |
UniProt ID : | P13765 |
Products Types
◆ Recombinant Protein | ||
HLA-DOB-190H | Recombinant Human HLA-DOB, His-tagged | +Inquiry |
HLA-DOB-13815H | Recombinant Human HLA-DOB, GST-tagged | +Inquiry |
◆ Lysates | ||
HLA-DOB-5504HCL | Recombinant Human HLA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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