Recombinant Human HLCS Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | HLCS-6636H |
Product Overview : | HLCS MS Standard C13 and N15-labeled recombinant protein (NP_000402) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 80.8 kDa |
AA Sequence : | MEDRLHMDNGLVPQKIVSVHLQDST LKEVKDQVSNKQAQILEPKPEPSLE IKPEQDGMEHVGRDDPKALGEEPKQ RRGSASGSEPAGDSDRGGGPVEHYH LHLSSCHECLELENSTIESVKFASA ENIPDLPYDYSSSLESVADETSPER EGRRVNLTGKAPNILLYVGSDSQEA LGRFHEVRSVLADCVDIDSYILYHL LEDSALRDPWTDNCLLLVIATRESI PEDLYQKFMAYLSQGGKVLGLSSSF TFGGFQVTSKGALHKTVQNLVFSKA DQSEVKLSVLSSGCRYQEGPVRLSP GRLQGHLENEDKDRMIVHVPFGTRG GEAVLCQVHLELPPSSNIVQTPEDF NLLKSSNFRRYEVLREILTTLGLSC DMKQVPALTPLYLLSAAEEIRDPLM QWLGKHVDSEGEIKSGQLSLRFVSS YVSEVEITPSCIPVVTNMEAFSSEH FNLEIYRQNLQTKQLGKVILFAEVT PTTMRLLDGLMFQTPQEMGLIVIAA RQTEGKGRGGNVWLSPVGCALSTLL ISIPLRSQLGQRIPFVQHLMSVAVV EAVRSIPEYQDINLRVKWPNDIYYS DLMKIGGVLVNSTLMGETFYILIGC GFNVTNSNPTICINDLITEYNKQHK AELKPLRADYLIARVVTVLEKLIKE FQDKGPNSVLPLYYRYWVHSGQQVH LGSAEGPKVSIVGLDDSGFLQVHQE GGEVVTVHPDGNSFDMLRNLILPKR RTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | HLCS holocarboxylase synthetase [ Homo sapiens (human) ] |
Official Symbol : | HLCS |
Synonyms : | HLCS; holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); holocarboxylase synthetase (biotin (proprionyl Coenzyme A carboxylase (ATP hydrolysing)) ligase), holocarboxylase synthetase (biotin [proprionyl Coenzyme A carboxylase (ATP hydrolysing)] ligase); biotin--protein ligase; HCS; biotin apo-protein ligase; biotin--[acetyl-CoA-carboxylase] ligase; biotin--[methylcrotonoyl-CoA-carboxylase] ligase; biotin--[methylmalonyl-CoA-carboxytransferase] ligase; holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase); |
Gene ID : | 3141 |
mRNA Refseq : | NM_000411 |
Protein Refseq : | NP_000402 |
MIM : | 609018 |
UniProt ID : | P50747 |
Products Types
◆ Recombinant Protein | ||
HLCS-2244H | Recombinant Human HLCS Protein, His-tagged | +Inquiry |
HLCS-4850H | Recombinant Human HLCS Protein, GST-tagged | +Inquiry |
Hlcs-491M | Recombinant Mouse Hlcs Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
HLCS-5491HCL | Recombinant Human HLCS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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