Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human HMGB1 Protein, GST-tagged

Cat.No. : HMGB1-4866H
Product Overview : Human HMGB1 full-length ORF ( AAH03378.1, 1 a.a. - 215 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 49.39 kDa
AA Sequence : MGKGDPKKPRGKMSSYAFFVQTCRE EHKKKHPDASVNFSEFSKKCSERWK TMSAKEKGKFEDMAKADKARYEREM KTYIPPKGETKKKFKDPNAPKRPPS AFFLFCSEYRPKIKGEHPGLSIGDV AKKLGEMWNNTAADDKQPYEKKAAK LKEKYEKDIAAYRAKGKPDAAKKGV VKAEKSKKKKEEEEDEEDEEDEEEE EDEEDEDEEEDDDDE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : HMGB1 high mobility group box 1 [ Homo sapiens ]
Official Symbol : HMGB1
Synonyms : HMGB1; high mobility group box 1; high mobility group (nonhistone chromosomal) protein 1 , high mobility group box 1 , HMG1; high mobility group protein B1; Amphoterin; DKFZp686A04236; high mobility group protein 1; HMG3; SBP 1; Sulfoglucuronyl carbohydrate binding protein; HMG-1; high-mobility group box 1; high-mobility group (nonhistone chromosomal) protein 1; HMG1; SBP-1;
Gene ID : 3146
mRNA Refseq : NM_002128
Protein Refseq : NP_002119
MIM : 163905
UniProt ID : P09429

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Why is HMGB1 protein associated with tumors? 11/07/2019

This protein can promote tumor growth, invasion and angiogenesis, and plays an important role in tumor immune evasion.

Is HMGB1 protein involved in tumor metastasis? 11/05/2019

Yes, HMGB1 protein plays an important role in tumor metastasis, particularly by promoting invasion of tumor cells and migration of the hematopoietic system.

What is the association between HMGB1 protein and cardiovascular disease? 10/02/2019

Is involved in inflammatory response, vascular damage, and thrombosis in cardiovascular disease and may be associated with myocardial ischemia-reperfusion injury.

What is the effect of HMGB1 protein on the immune system? 08/31/2019

HMGB1 protein can promote the activation, chemotaxis and inflammatory response of immune cells, and is also involved in regulating the balance of autoimmune response.

What role does HMGB1 play in diabetes? 08/21/2019

HMGB1 protein is associated with processes such as chronic inflammation and insulin resistance in diabetes and may be a potential target for treatment and prevention.

Does HMGB1 play a role in liver disease? 08/15/2019

The protein is involved in pathological processes such as liver fibrosis, hepatitis, and liver cancer in liver disease and may be a target for therapeutic strategies.

Customer Reviews (3)

Write a review
Reviews
09/22/2021

    Broad storage conditions of HMGB1ins make the experimental process more stable and reliable, which provides a strong guarantee for scientific research.

    05/02/2020

      I found that tHMGB1 exhibited very good stability during storage, which allowed us to perform experiments easily and obtain reliable results.

      01/11/2019

        The anti-contamination ability of HMGB1 was excellent in Western blot, and the contamination problem in the experiment was avoided.

        Ask a Question for All HMGB1 Products

        Required fields are marked with *

        My Review for All HMGB1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends