| Description : |
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. |
| Source : |
HEK293 cells |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.2 |
| Molecular Mass : |
25.07kD |
| AA Sequence : |
MGKGDPNKPRGKMSSYAFFVQTCRE EHKKKHPDSSVNFAEFSKKCSERWK TMSAKEKSKFEDMAKSDKARYDREM KNYVPPKGDKKGKKKDPNAPKRPPS AFFLFCSEHRPKIKSEHPGLSIGDT AKKLGEMWSEQSAKDKQPYEQKAAK LKEKYEKDIAAYRAKGKSEAGKKGP GRPTGSKKKNEPEDEEEEEEEEDED EEEEDEDEEVDHHHHHH |
| Endotoxin : |
Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
| Purity : |
>95% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
