Recombinant Human HNRNPAB Protein, GST-tagged

• Cat.No.: HNRNPAB-4912H
• Product Overview: Human HNRPAB full-length ORF ( NP_004490.2, 1 a.a. - 285 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57 kDa
• AA Sequence: MSEAGEEQPMETTGATENGHEAVPE GESPAGAGTGAAAGAGGATAAPPSG NQNGAEGDQINASKNEEDAGKMFVG GLSWDTSKKDLKDYFTKFGEVVDCT IKMDPNTGRSRGFGFILFKDAASVE KVLDQKEHRLDGRVIDPKKAMAMKK DPVKKIFVGGLNPEATEEKIREYFG EFGEIEAIELPMDPKLNKRRGFVFI TFKEEEPVKKVLEKKFHTVSGSKCE IKVAQPKEVYQQQQYGSGGRGNRNR GNRGSGGGGGGGGQGSTNYGKSQRR GGHQNNYKPY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HNRNPAB heterogeneous nuclear ribonucleoprotein A/B [ Homo sapiens ]
• Official Symbol: HNRNPAB
• Synonyms: ABBP1; HNRPAB
• Gene ID: 3182
• mRNA Refseq: NM_031266
• Protein Refseq: NP_112556
• MIM: 602688
• UniProt ID: Q99729