Recombinant Human HNRPDL Protein, GST-tagged

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Recombinant Human HNRPDL Protein, GST-tagged

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Cat.No. : HNRPDL-4915H
Product Overview : Human HNRPDL full-length ORF (AAH11714.1, 1 a.a. - 420 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein encoded by this gene is similar to its family member HNRPD. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 72.8 kDa
AA Sequence : MEVPPRLSHV PPPLFPSAPA TLASRSLSHW RPRPPRQLAP LLPSLAPSSA RQGARRAQRH VTAQQPSRLA GGAAIKGGRR RRPDLFRRHF KSSSIQRSAA AAAATRTARQ HPPADSSVTM EDMNEYSNIE EFAEGSKINA SKNQQDDGKM FIGGLSWDTS KKDLTEYLSR FGEVVDCTIK TDPVTGRSRG FGFVLFKDAA SVDKVLELKE HKLDGKLIDP KRAKALKGKE PPKKVFVGGL SPDTSEEQIK EYFGAFGEIE NIELPMDTKT NERRGFCFIT YTDEEPVKKL LESRYHQIGS GKCEIKVAQP KEVYRQQQQQ QKGGRGAAAG GRGGTRGRGR GQGQNWNQGF NNYYDQGYGN YNSAYGGDQN YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : HNRPDL heterogeneous nuclear ribonucleoprotein D-like [ Homo sapiens ]
Official Symbol : HNRPDL
Synonyms : heterogeneous nuclear ribonucleoprotein D-like; 5037; Ensembl:ENSG00000152795; heterogeneous nuclear ribonucleoprotein D-like;hnRNP DL;hnRNP D-like;protein laAUF1;JKT41-binding protein;AU-rich element RNA-binding factor;A+U-rich element RNA binding factor; HNRNP; JKTBP; JKTBP2; laAUF1
Gene ID : 9987
mRNA Refseq : NM_001207000
Protein Refseq : NP_001193929
MIM : 607137
UniProt ID : O14979

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