Recombinant Human HOXA7 Protein, C-MYC/DDK-tagged

• Cat.No.: HOXA7-22H
• Product Overview: Recombinant human HOXA7 protein with a C-MYC/DDK-tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&Myc
• Description: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.
• Molecular Mass: 25.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Publications:
  Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer (2019)

Gene Information

• Gene Name: HOXA7
• Official Symbol: HOXA7 homeobox A7 [ Homo sapiens (human) ]
• Synonyms: HOXA7; homeobox A7; ANTP; HOX1; HOX1A; HOX1.1; homeobox protein Hox-A7; homeo box A7; homeobox protein HOX-1A; homeobox protein Hox 1.1
• Gene ID: 3204
• mRNA Refseq: NM_006896
• Protein Refseq: NP_008827
• MIM: 142950
• UniProt ID: P31268