Recombinant Human HPF1 Protein (1-346 aa), His-SUMO-Myc-tagged
Cat.No. : | HPF1-2397H |
Product Overview : | Recombinant Human HPF1 Protein (1-346 aa) is produced by E. coli expression system. This protein is fused with a 10xHis-SUMO tag at the N-terminal and a Myc tag at the C-terminal. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2: interacts with PARP1 and PARP1 and is able to change amino acid specificity toward serine. Promotes histone serine ADP-ribosylation in response to DNA damage, limiting DNA damage-induced PARP1 hyper-automodification, and ensuring genome stability. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO-Myc |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 59.4 kDa |
Protein length : | 1-346 aa |
AA Sequence : | MVGGGGKRRPGGEGPQCEKTTDVKK SKFCEADVSSDLRKEVENHYKLSLP EDFYHFWKFCEELDPEKPSDSLSAS LGLQLVGPYDILAGKHKTKKKSTGL NFNLHWRFYYDPPEFQTIIIGDNKT QYHMGYFRDSPDEFPVYVGINEAKK NCIIVPNGDNVFAAVKLFLTKKLRE ITDKKKINLLKNIDEKLTEAARELG YSLEQRTVKMKQRDKKVVTKTFHGA GLVVPVDKNDVGYRELPETDADLKR ICKTIVEAASDEERLKAFAPIQEMM TFVQFANDECDYGMGLELGMDLFCY GSHYFHKVAGQLLPLAYNLLKRNLF AEIIEEHLANRSQENIDQLAA |
Purity : | > 85% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | HPF1 histone PARylation factor 1 [ Homo sapiens (human) ] |
Official Symbol : | HPF1 |
Synonyms : | HPF1; C4orf27; |
Gene ID : | 54969 |
mRNA Refseq : | NM_017867 |
Protein Refseq : | NP_060337 |
UniProt ID : | Q9NWY4 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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