Recombinant Human HR, GST-tagged
Cat.No. : | HR-13933H |
Product Overview : | Recombinant Human HR protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs, U2HR, cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 351-700a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HR hairless homolog (mouse) [ Homo sapiens ] |
Official Symbol : | HR |
Synonyms : | HR; hairless homolog (mouse); ALUNC, hairless (mouse) homolog; AU; ALUNC; |
Gene ID : | 3264 |
MIM : | 602302 |
UniProt ID : | O43593 |
Chromosome Location : | 8p12 |
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HR-1961R | Recombinant Rhesus Macaque HR Protein, His (Fc)-Avi-tagged | +Inquiry |
HR-5022H | Recombinant Human HR Protein, GST-tagged | +Inquiry |
HR-4313M | Recombinant Mouse HR Protein, His (Fc)-Avi-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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