Recombinant Human HRH1

Cat.No. : HRH1-27712TH
Product Overview : Recombinant full length Human Histamine H1 Receptor with N terminal FLAG tag and C terminal His tag, coexpressed with RGS4 , prepared from Sf9 cells coinfected with Human Histamine H1 Receptor and RGS4-encoding baculoviruses.
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Description : Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Conjugation : FLAG,His
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Tag : His&Flag
Gene Name : HRH1 histamine receptor H1 [ Homo sapiens ]
Official Symbol : HRH1
Synonyms : HRH1; histamine receptor H1; histamine H1 receptor;
Gene ID : 3269
mRNA Refseq : NM_000861
Protein Refseq : NP_000852
MIM : 600167
Uniprot ID : P35367
Chromosome Location : 3p25
Pathway : Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function : G-protein coupled receptor activity; histamine binding; histamine receptor activity; receptor activity; signal transducer activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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