Recombinant Human HSA-Interferon Alpha-2b
Cat.No. : | INFA2-04H |
Product Overview : | Recombinant HSA fusion Interferon alpha-2b produced inP. Pichiais a single, non-glycosylated, polypeptide chain having a molecular mass of 85.7 kDa |
- Specification
- Gene Information
- Related Products
Cat. No. : | INFA2-04H |
Description : | At least 23 different variants of Interferon-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxyl-terminal end. |
Purity : | >98% as determined by SDS-PAGE , RP-HPLC and FPLC. |
Formulation : | Lyophilized from a (3mg/ml) solution in containing 2.4mg Tris base and 8.8mg sodium chloride. |
Specific Activity : | The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 5.0 x 106IU/mg. |
Endotoxin : | Less than 0.1 ng/µg (IEU/µg) of HSA-IFN-alpha 2b. |
Reconstitution : | It is recommended to reconstitute the lyophilized HSA-IFN alpha-2b in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Storage : | Lyophilized HSA-IFN alpha-2b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HSA-IFN alpha-2b should be stored at 4°C between 2-7 days and for future use below -18°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freeze-thaw cycles. |
Gene Name : | IFNA2 |
Synonyms : | IFNA; INFA2; MGC125764; MGC125765; Leukocyte interferon; B cell interferon, Type I interferon; IFNA2; IFN-α |
Gene ID : | 3440 |
mRNA Refseq : | NM_000605.2 |
Protein Refseq : | NP_000596.2 |
MIM : | 147562 |
UniProt ID : | P01563 |
Chromosome Location : | 9p22 |
Pathway : | Antigen processing and presentation; Cytokine-cytokine receptor interaction ;Jak-STAT signaling pathway ;KEGG pathway: Natural killer cell mediated cytotoxicity ;Regulation of autophagy ;Toll-like receptor signaling pathway |
Function : | interferon-alpha/beta receptor binding |
Products Types
◆ Recombinant Protein | ||
Ifna2-89M | Active Recombinant Mouse Ifna2 protein(Cys24-Glu190), hFc-tagged | +Inquiry |
IFNA2-2517H | Recombinant Human IFNA2 protein(61-180 aa), C-His-tagged | +Inquiry |
IFNA2-114H | Active Recombinant Human IFN-alpha 2b Protein | +Inquiry |
IFNA2-1261H | Acitve Recombinant Human IFNA2 protein(Cys24-Glu188) | +Inquiry |
IFNA2-075H | Active Recombinant Human IFNA2 Protein | +Inquiry |
◆ Lysates | ||
IFNA2-1634MCL | Recombinant Mouse IFNA2 cell lysate | +Inquiry |
IFNA2-954CCL | Recombinant Cynomolgus IFNA2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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