Recombinant Human HSPA1B

• Cat.No.: HSPA1B-29402TH
• Product Overview: Recombinant full length Human Hsp70, MWt 70kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
• Tissue specificity: HSPA1B is testis-specific.
• Biological activity: ATPase assay: positive
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 1X Dulbeccos PBS
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the heat shock protein 70 family.
• Full Length: Full L.

Gene Information

• Gene Name: HSPA1B heat shock 70kDa protein 1B [ Homo sapiens ]
• Official Symbol: HSPA1B
• Synonyms: HSPA1B; heat shock 70kDa protein 1B; heat shock 70kD protein 1B; heat shock 70 kDa protein 1A/1B; HSP70 2
• Gene ID: 3304
• mRNA Refseq: NM_005346
• Protein Refseq: NP_005337
• MIM: 603012
• Uniprot ID: P08107
• Chromosome Location: 6p21.3
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem
• Function: ATP binding; nucleotide binding; protein N-terminus binding; protein binding; protein binding involved in protein folding