Recombinant Human HUWE1, GST-tagged
Cat.No. : | HUWE1-136H |
Product Overview : | Recombinant human HUWE1 (amino acid residues 3760-4374), with N-terminal GST, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | The enzymes of the ubiquitylation pathway play a pivotal role in a number of cellular processes including the regulated and targeted proteasome-dependent degradation of substrate proteins. Three classes of enzymes are involved in the process of ubiquitylation; activating enzymes (E1s), conjugating enzymes (E2s) and protein ligases (E3s). Hect, Uba, and Wwe Domains containing protein 1 (HUWE1) is a member of the Homologous to the E6AP Carboxyl Terminus (HECT) E3 protein ligase family and cloning of the human gene was first described by (Liu et al., 2005). |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol |
Molecular Mass : | ~97kDa |
Storage : | 12 months at -70°C. Avoid multiple freeze/thaw cycles. |
Concentration : | 0.5mg/ml |
Gene Name : | HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase [ Homo sapiens ] |
Official Symbol : | HUWE1 |
Synonyms : | HUWE1; HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase; HECT, UBA and WWE domain containing 1; E3 ubiquitin-protein ligase HUWE1; Ib772; KIAA0312; UREB1; ARF-binding protein 1; URE-binding protein 1; BJ-HCC-24 tumor antigen; large structure of UREB1; HECT domain protein LASU1; Mcl-1 ubiquitin ligase E3; upstream regulatory element-binding protein 1; homologous to E6AP carboxyl terminus homologous protein 9; MULE; LASU1; HECTH9; URE-B1; ARF-BP1; HSPC272; |
Gene ID : | 10075 |
mRNA Refseq : | NM_031407 |
Protein Refseq : | NP_113584 |
MIM : | 300697 |
UniProt ID : | Q7Z6Z7 |
Chromosome Location : | Xp11.22 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; |
Function : | DNA binding; acid-amino acid ligase activity; binding; ligase activity; protein binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
HUWE1-2000R | Recombinant Rhesus Macaque HUWE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HUWE1-14015H | Recombinant Human HUWE1, GST-tagged | +Inquiry |
HUWE1-14016H | Recombinant Human HUWE1, GST-tagged | +Inquiry |
HUWE1-2179R | Recombinant Rhesus monkey HUWE1 Protein, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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