Recombinant Human IDH2 Protein, DDK-tagged
Cat.No. : | IDH2-046H |
Product Overview : | Purified recombinant protein of Homo sapiens isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2) and mutant(R172K) heterodimer, with C-terminal 6xHis and DDK tags, expressed in sf9 cells. |
- Specification
- Gene Information
- Related Products
Description : | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]. |
Source : | Insect cell |
Species : | Human |
Tag : | DDK |
Molecular Mass : | 46.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 50mM Tris-HCl, pH 8.0, 100mM glycine, 150mM NaCl, 10% glycerol. |
Gene Name : | IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial [ Homo sapiens ] |
Official Symbol : | IDH2 |
Synonyms : | IDH2; isocitrate dehydrogenase 2 (NADP+), mitochondrial; isocitrate dehydrogenase [NADP], mitochondrial; NADP(+)-specific ICDH; oxalosuccinate decarboxylase; IDH; IDP; IDHM; IDPM; ICD-M; D2HGA2; mNADP-IDH; |
Gene ID : | 3418 |
mRNA Refseq : | NM_002168 |
Protein Refseq : | NP_002159 |
MIM : | 147650 |
UniProt ID : | P48735 |
Products Types
◆ Recombinant Protein | ||
IDH2-2013R | Recombinant Rhesus Macaque IDH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IDH2-994H | Recombinant Human IDH2 Protein, His-tagged | +Inquiry |
IDH2-4410M | Recombinant Mouse IDH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IDH2-2641R | Recombinant Rat IDH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IDH2-355C | Recombinant Cynomolgus Monkey IDH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IDH2-5306HCL | Recombinant Human IDH2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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