| Cat.No. : |
IFITM2-001H |
| Product Overview : |
Recombinant Human IFITM2 Protein (1-132 aa (full-length)) with 6xHis-GST tags was expressed in E. coli. |
| Description : |
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His-GST |
| Molecular Mass : |
43.2 kDa |
| Protein length : |
1-132 |
| Purity : |
>90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB). |
| Applications : |
ELISA, Western Blot, Antibody Production, Protein array |
| Quality Control Test : |
10% SDS-PAGE stained with Coomassie Blue (CB), immunoblotting with anti-GST(WB) and peptide fingerprinting by MALDI-TOF mass spectrometry. |
| Storage : |
Store working aliquots at 4 centigrade for up to one week. For extended storage, conserve at −80 centigrade. |
| Expiry : |
12 months from the date of purchase, if it is properly stored. |
| Storage Buffer : |
20mM Sodium Phosphate, 0.5M NaCl, 0.15M imidazole, pH 7.4. No preservatives added. |
| Shipping : |
Dry Ice |
| Figure : |
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